师资队伍

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杨易

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姓名:杨易

职称:教授

职务:

联系电话:0951-2062976

E-mail:yangyi@nxu.edu.cn

研究生招生方向:动物生物学

个人简介

科研领域

代表性论文

杨易,教授,博士,博士生/硕士生导师,生物科学专业负责人,从事遗传学及生殖生物学教学科研工作。中国遗传学会教育教学分会委员,“哺乳动物生殖技术新理论”自治区创新团队核心成员,宁夏生物学会理事,宁夏干细胞协会监事。承担本科生《遗传学》、研究生《生殖生理学》等课程的教学任务;主讲遗传学课程认定为首批国家线上线下混合式一流课程,人类遗传探秘认定为自治区线上一流课程。主持完成国家自然科学基金1项,国家重点研发子课题1项,先后参与完成国家级省部级课题7项,在国内外学术期刊发表论文50余篇,SCI收录14篇。先后荣获宁夏自然科学优秀学术论文二等奖和三等奖各1项,先后荣获2015年全国高校(生命科学类)微课比赛“教学风采奖”1项,2017年全国高校(生命科学类)微课比赛三等奖1项,第十五届宁夏自然科学优秀学术论文二等奖,宁夏大学“第九届教学优秀奖”,宁夏大学“第六届青年教师教学基本功大赛三等奖”,指导完成宁夏大学大学生创新创业项目10项,全国大学生生命科学竞赛(科学探究类)4项,多次获生命科学学院“最受学生欢迎教师”荣誉称号。

1.Boli Ma#,Xueyi Nie,Lei Liu,Mengyuan Li,Qi Chen,Yueyang Liu,Yuxin Hou,Yi Yang*,Jinrui Xu*. GSK2656157, a PERK Inhibitor, Alleviates Pyroptosis of Macrophages Induced by Mycobacterium Bacillus Calmette-Guerin Infection.International journal of Molecular Sciences,2023,24(22):1-13.doi: 10.3390/ijms242216239

2. Lifan Zhang#,Yabo Ma#,Xianguo Xie,Changzheng Du,Yan Zhang, Shaogang Qin,Jinrui Xu,Chao Wang,Yi Yang*, Guoliang Xia*. Human Pluripotent Stem Cell-Mesenchymal Stem Cell-Derived Exosomes Promote Ovarian Granulosa Cell Proliferation and Attenuate Cell Apoptosis Induced by Cyclophosphamide in a POI-like Mouse Model.Molecules,2023, 28(5): 1-18.doi.org/10.3390/molecules28052112

3.Yabo Ma#, Changzheng Du#, Xianguo Xie#,Yan Zhang, Chao Wang, Jinrui Xu ,Guoliang Xia,Yi Yang*. To explore the regulatory role of Wnt/P53/Caspase3 signal in mouse ovarian development based on LFQ proteomics.Journal of Proteomics, 2023, 272: 1-9.doi: 10.1016/j.jprot.2022.104772. Epub 2022 Nov 19.

4.Yan Zhang#,Xianguo Xie#,Yabo Ma#, Changzheng Du, Yuan Jiao,Guoliang Xia, Jinrui Xu*,Yi Yang*. Cyproterone Acetate Mediates IRE1 α Signaling Pathway to Alleviate Pyroptosis of Ovarian Granulosa Cells Induced by Hyperandrogen.Biology (Basel), 2022, 11(12): 1-17.doi: 10.3390/biology11121761.

5.Qi Chen#,Xuedi Zheng,Yong Li, Boli Ma,Xueyi Nie,Mengyuan Li, Yueyang Liu,Jinrui Xu*,Yi Yang*.Wnt5a regulates autophagy in Bacille Calmette-Guérin (BCG)-Infected pulmonary epithelial cells.Microbial Pathogenesis,2022, 173: 1-14.doi: 10.1016/j.micpath.2022.105826.

6.Xu J#, Zhou Y#,Yang Y#,Lv C, Liu X, Wang Y. Involvement of ABC-transporters and acyltransferase 1 in intracellular cholesterol-mediated autophagy in bovine alveolar macrophages in response to the Bacillus Calmette-Guerin (BCG) infection. BMC Immunol. 2020;21(1):26.doi: 10.1186/s12865-020-00356-x.

7.Yi Yang#,Yingfei Sun#, Jinrui Xu#, Kangda Bao, Meihui Luo, Xiaoming Liu* and Yujiong Wang*. Epithelial Cells Attenuate Toll-Like Receptor-Mediated Inflammatory Responses in Monocyte-Derived Macrophage-Like Cells to Mycobacterium tuberculosis by Modulating the PI3K/Akt/mTOR Signaling Pathway. Mediators of Inflammation, 2018, 3685948.doi: 10.1155/2018/3685948. eCollection 2018.

8.Yi Yang#,Jinrui Xu, Yujiong Wang, Xiaoming Liu*. Polymorphic association ofTCF7L2 gene with the susceptibility to type 2 diabetes mellitus in a Chinese Hui population. Genetics and Molecular Research, 2015, 14 (3): 10064-10071.

9.Yi Yang#, Jinrui Xu, Xiaoming Liu, Jin Zhou, Bo Yang, Min Li and Yujiong Wang*, Polymorphism of +2836 G>A in the apoE gene are strongly associated with the susceptibility to essential hypertension in the Chinese Hui population,Genetic and Molecular Research, 2014, 13(1): 1212-1219.

10.Li, Mengyuan#, Yueyang Liu, Xueyi Nie, Boli Ma, Yabo Ma, Yuxin Hou,Yi Yang, Jinrui Xu*, and Yujiong Wang*. 2023. S100A4 Promotes BCG-Induced Pyroptosis of Macrophages by Activating the NF-κB/NLRP3 Inflammasome Signaling Pathway International Journal of Molecular Sciences. 2023, 24(16), 12709; https://doi.org/10.3390/ijms241612709

11.Nie, Xueyi#, Boli Ma, Lei Liu, Xiaotan Yuan, Mengyuan Li, Yueyang Liu, Yuxin Hou,Yi Yang, Jinrui Xu, Yujiong Wang. Endoplasmic Reticulum Stress Mediated NLRP3 Inflammasome Activation and Pyroptosis in THP-1 Macrophages Infected with Bacillus Calmette-Guérin" International Journal of Molecular Sciences. 2023, 24(14), 11692; https://doi.org/10.3390/ijms241411692.

12.Zheng X#, Li M, Chen Q, Ma B, Nie X, Liu Y,Yang Y, Xu J*, Wang Y*. Ror2-mediated cholesterol accumulation regulates autophagic activity within BCG-infected macrophages. Microb Pathog. 2022 Jun;167:105564. doi: 10.1016/j.micpath.2022.105564. Epub 2022 May 7. PMID: 35537593.

13.He M#, Zhang T#,Yang Yand Chao Wang* (2021) Mechanisms of Oocyte Maturation and Related Epigenetic Regulation. Front Cell Dev Biol. 2021 9:654028

14.Tuo Zhang#, Meina He#, Lihua Zhao#,Shaogang Qin, Zijian Zhu, Xinhua Du, Bo Zhou,Yi Yang, Xinfeng Liu, Guoliang Xia, Tengxiang Chen, Yuanxi Wang, Hua Zhang*, Chao Wang* HDAC6 regulates primordial follicle activation through mTOR signaling pathway. Cell Death Dis. 2021 3

15.Hao Yan#, Jia Wen, Tuo Zhang, Wenying Zheng, Meina He, Kun Huang, Qirui Guo, Qian Chen,Yi Yang,Guangcun Deng, Jinrui Xu, Zhiqing Wei, Hua Zhang*, Guoliang Xia*, Chao Wang*. Oocyte-derived E-cadherin acts as a multiple functional factor maintaining the primordial follicle pool in mice. Cell Death Dis. 2018 10:160

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